Increased Oxygen Consumption in Human Adipose Tissue From the “Brown Adipose Tissue” Region
نویسندگان
چکیده
منابع مشابه
Gene expression in human brown adipose tissue.
Brown adipose tissue (BAT) has profound effects on body weight and metabolism in rodents. Recent reports show that human adults have significant amounts of BAT. Our aim was to study the gene expression profile of human BAT. Biopsies of adipose tissue with brown-red color and subcutaneous white adipose tissue (WAT) were obtained from 24 patients undergoing surgery in the thyroid region. Intrasca...
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Obesity remains a major biomedical challenge with its associated diseases, particularly insulin resistance and type 2 diabetes, imposing a substantial and increasing burden on health care systems. In the U.S., one-third of adults are classed as obese (BMI $30), while in the U.K., which has one of the highest incidence rates in Europe, 25% are obese. Conceptually, the treatment of obesity is sim...
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Brown adipose tissue (BAT) is known to be responsible for heat production in newborn and adult hibernating mammals. In rats and mice, BAT has been demonstrated to possess a much higher glycerokinase activity than white adipose tissue (WAT). It has been speculated that this high activity may cause the futile cycle of triglyceride breakdown and resynthesis to be activated, thus contributing to he...
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Obesity is currently a global pandemic, and is associated with increased mortality and co-morbidities including many metabolic diseases. Obesity is characterized by an increase in adipose mass due to increased energy intake, decreased energy expenditure, or both. While white adipose tissue is specialized for energy storage, brown adipose tissue has a high concentration of mitochondria and uniqu...
متن کاملAnatomical Locations of Human Brown Adipose Tissue
We will review information about and present hypotheses as to the anatomy of brown adipose tissue (BAT). Why is it located where it is in humans? Its anatomical distribution is likely to confer survival value by protecting critical organs from hypothermia by adaptive thermogenesis. Ultimately, the location and function will be important when considering therapeutic strategies for preventing and...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2013
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2013-1348